Product Name: Diisopropylbenzene
Chemical Formula: C12H18
Synonyms: 1,3-Diisopropylbenzene, 1,4-Diisopropylbenzene, m-Diisopropylbenzene, p-Diisopropylbenzene
CAS Number: 25321-09-9
Manufacturer: Major chemical suppliers and specialty companies with global distribution
Recommended Use: Organic synthesis, chemical intermediate, solvent
Emergency Contact: Provided by manufacturer or chemical supplier in transport documentation
GHS Classification: Flammable liquid (Category 3), Acute toxicity (oral, Category 4), Skin irritation (Category 2), Eye irritation (Category 2A)
Label Elements: Flame symbol, Exclamation mark symbol, hazard and precautionary statements
Hazards: Vapors may form explosive mixtures with air, ingestion or inhalation can cause respiratory and nervous system effects, skin and eye contact may produce irritation, prolonged exposure can impact liver and kidneys
Route of Exposure: Skin, eyes, inhalation, ingestion
Potential Health Effects: Dizziness, headache, nausea, drowsiness, dermatitis, respiratory tract irritation
Target Organs: Central nervous system, skin, liver, eyes
Environmental Hazards: Harmful to aquatic life with long lasting effects non-rapidly degradable in the environment
Chemical Name: Diisopropylbenzene
Concentration: >98%
CAS Number: 25321-09-9
Impurities: Trace levels of mono-isopropylbenzene, other alkylated benzenes
Molecular Weight: 162.27 g/mol
Structural Formula: Benzene ring with two isopropyl groups as substituents
Inhalation: Move to fresh air, keep at rest, monitor breathing, call for medical attention if symptoms persist
Skin Contact: Rinse skin thoroughly with soap and water, strip contaminated clothing, seek medical help if irritation develops
Eye Contact: Rinse with plenty of water for at least 15 minutes, remove contact lenses if present, seek medical assessment for persistent discomfort
Ingestion: Do not induce vomiting, rinse mouth with water, provide water if conscious, seek emergency medical treatment right away, risk of aspiration into lungs
Symptoms: Irritation, redness, dizziness, confusion, headache, nausea, possible loss of coordination
Special Note to Physician: Treat symptomatically, monitor for respiratory distress or aspiration pneumonia
Flammability: Flammable liquid and vapor, can ignite at room temperature
Suitable Extinguishing Media: Alcohol-resistant foam, carbon dioxide, dry chemical, water spray (do not use direct water jet)
Hazards from Combustion: May produce carbon monoxide, carbon dioxide, dense, toxic smoke and irritating vapors
Protective Equipment: Full protective clothing, self-contained breathing apparatus, keep upwind
Fire Precautions: Move containers from fire area if safe, cool with water spray, prevent runoff into drains or waterways
Explosion Risk: Vapors heavier than air, may travel long distances, ignite by flashback at ignition source
Personal Precautions: Evacuate area, eliminate all ignition sources, ensure ventilation, wear appropriate PPE including gloves, goggles, and respirator in confined areas
Environmental Precautions: Prevent substance from entering drains, surface water, and soil
Containment and Cleanup: Use inert absorbing material such as sand or earth, collect in labeled containers for proper disposal, ventilate spill area, wash site after removal with suitable detergent
Cleanup Methods: Shovel and transfer spilled material to appropriate containers for recovery or disposal, do not flush into sewers, avoid dust and vapor formation
Reporting: Notify local authorities if significant release threatens environmental safety
Handling: Maintain closed containers, avoid vapor inhalation, prevent skin and eye contact, use with proper exhaust ventilation, remove sources of static discharge and ignition, practice good hygiene
Storage: Store in a cool, dry, well-ventilated area separate from oxidizers, acids, and sources of heat or flame, use containers made from compatible materials like steel or glass, keep tightly capped
Hygiene Practices: Wash hands after use, prohibit eating, drinking, or smoking nearby, launder contaminated clothing before re-use
Special Requirements: Use grounding for containers and equipment, label storage vessels clearly
Occupational Exposure Limits: No established US OSHA or ACGIH limits, minimize exposure by engineering controls
Engineering Controls: Local exhaust ventilation, mechanical ventilation for confined spaces
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles or face shield, lab coat/testing garments, respiratory protection if vapor formation crosses safe thresholds or in poorly ventilated spaces
Environmental Controls: Prevent accidental spillage into waters, employ secondary containment for storage areas
Appearance: Clear, colorless to pale yellow liquid
Odor: Aromatic, hydrocarbon-like
Odor Threshold: Noticeable at low concentrations
pH: Not applicable (non-aqueous)
Melting Point: -45°C
Boiling Point: 218 – 224°C
Flash Point: 82°C (closed cup)
Evaporation Rate: Below water’s rate
Flammability: Flammable liquid
Vapor Pressure: 0.1 mm Hg at 20°C
Vapor Density: >1 (air = 1)
Relative Density: 0.86 – 0.87 g/cm³
Solubility: Practically insoluble in water, soluble in organic solvents
Partition Coefficient n-octanol/water (Log Kow): 5.1
Autoignition Temperature: 420°C
Decomposition Temperature: No decomposition below boiling point
Viscosity: Less than 2 mPa.s at 25°C
Chemical Stability: Stable under normal conditions, will not polymerize
Reactivity: Reacts with strong oxidizers, acids, peroxides
Conditions to Avoid: Heat, flame, sparks, static discharge, incompatible substances
Incompatible Materials: Strong oxidizing agents like nitric acid, chlorine, peroxides, strong acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, potentially hazardous aromatic compounds under fire
Risk of Hazardous Polymerization: Does not occur
Acute Toxicity (Oral): LD50 (rat) is estimated at around 1800 mg/kg
Acute Toxicity (Dermal): LD50 (rabbit) information limited; expected moderately toxic
Acute Toxicity (Inhalation): Data incomplete, aromatic hydrocarbons can cause central nervous system effects
Skin Corrosion/Irritation: Can cause redness, irritation, dryness
Eye Damage/Irritation: May cause irritation, tearing, redness
Respiratory Sensitization: Vapors may irritate nose, throat, lungs
Carcinogenicity: Not listed as a confirmed carcinogen by IARC, NTP, OSHA
Mutagenicity: Not considered mutagenic, according to standard tests
Reproductive Toxicity: No definitive studies, keep exposure minimal
Chronic Effects: Long term overexposure may damage liver, kidneys, central nervous system
Aquatic Toxicity: Harmful to aquatic organisms, fish LC50 (96 h): <10 mg/L, can bioaccumulate in aquatic life
Persistence and Degradability: Slow to degrade, considered persistent in the environment
Bioaccumulative Potential: High partition into organic phases, bioaccumulation likely
Mobility in Soil: Moderately mobile, expected to adsorb to soil particles
Environmental Disposal Concerns: Long-term pollution possible, contributes to environmental contamination
Other Adverse Effects: May cause disruption in aquatic and soil micro-organism populations
Disposal Methods: Incinerate under controlled conditions in accordance with local and national environmental agencies
Waste Containment: Place residues in approved containers, label with contents and hazard information
RCRA Status: Not listed as hazardous waste, but should not enter drains, water courses, or be disposed with household waste
Recycling: Consult an environmental professional for recycling or energy recovery measures where possible
Contaminated Packaging: Clean before disposal, follow hazardous waste guidelines for disposal
UN Number: UN2329
Proper Shipping Name: Diisopropylbenzene
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Label Requirements: Flammable Liquid
Transport Notes: Avoid extreme temperatures, keep away from sources of ignition, follow local and international transport guidelines, including IMDG, IATA, and DOT
Special Provisions: Emergency response information included with shipment
OSHA HazCom: Hazardous chemical, subject to standard communication requirements
US EPA TSCA: Listed on the Toxic Substances Control Act Inventory
EU REACH: Substance registered; safety data required for volumes over 1 ton/year
Canadian DSL/NDSL: Listed on the Domestic Substances List
Other National Inventories: Covered under Australian AICS, Chinese IECSC, Japanese ENCS, Korean ECL
Department of Transportation: Regulated for transport as flammable liquid
Other Regulations: Workplace and environmental regulations require risk assessment and safety documentation where stored or handled
